Department of Psychiatry and Neuroscience
University of Florida College of Medicine
Dr. Setlow is an alumnus of the Center for the Neurobiology of Learning and Memory. Much of the research in the Setlow laboratory concerns interactions between decision-making processes and drugs of abuse. In some of their research, they investigate the long-term effects of chronic exposure to drugs of abuse on cognitive outcomes, with a particular focus on different types of decision-making processes (for example, risky and impulsive decision-making) and the neural mechanisms underlying drug-induced alterations in such processes. In other research, they investigate how individual differences in risky and impulsive decision-making predict propensity for future drug use. In all of this research, they use a variety of techniques (e.g., behavioral/cognitive testing, behavioral pharmacology, biochemistry, in vivo electrophysiology) to identify mechanisms that mediate relationships between decision-making and drug abuse, with the ultimate goal of identifying therapeutic targets for both maladaptive decision-making and addiction.