Understanding memory and helping to develop treatments for those with memory problems are two connected ‘Grand Challenges’ of contemporary neuroscience.

The primary research interest of my group is the neurobiology of learning and memory, and specifically whether and how memory depends on the ‘plasticity’ of the brain. We seek an understanding of memory mechanisms at the level of synapses, neurons, brain systems, and the underlying physiology that plays out in relevant networks.

We develop and use analytically powerful behavioral protocols (e.g. the ‘event arena’), together with neuropharmacological, optogenetic and molecular-engineering tools.

We also have an active interest in the translation of concepts and techniques from this fundamental work to develop new therapeutics targeted at Alzheimer's Disease and neurodevelopmental disorders.