CNLM Colloquium UCI Spotlight Series

Join the CNLM in a hybrid colloquium featuring Dr. Leslie Thompson, Professor of Psychiatry & Human Behavior at UC Irvine.

Huntington’s disease research and therapeutics; the long winding road

Huntington’s disease is a devastating neurodegenerative disease that typically strikes in the prime of life with no disease modifying treatment. It is caused by a repeat expansion within the coding region of the protein Huntingtin which is expressed throughout the body and is required for a vast array of cellular processes. The disease mutation causes both a gain of function and loss of normal function which adds significant complexity to understanding disease mechanisms and advancing therapeutics. In this talk I will describe three vignettes relating to disease mechanisms and therapeutic approaches undertaken in the laboratory.

This event will be held in-person in the Herklotz Conference Center and virtually via Zoom.