Dr. Gremel is interested in volitional control over behavior and its alteration in Alcohol Use Disorders (AUD). The Gremel Lab takes a multi-pronged approach largely in mice, investigating both the continuous and dynamic nature of experience-guided behavior as well as the neural bases for such control. To this end, they use a combination of sophisticated behavioral and computational analyses, with genetic, pharmacological, in vivo imaging and recording techniques, as well as ex vivo physiology experiments. They aim to identify neural mechanisms allowing the brain to use continuous experiential information to control one’s behavior.
Key Research Areas:
Action Control, Goal-directed, Orbital Frontal Cortex, Dorsal Striatum, Alcohol, Habit