Imagine that you smell some delicious foods as you walk down a street – and suddenly you start to recall the good old days you had that dish when you were small. This is a typical example showing the powerful link between memory and olfaction – the sense of smell. But how do neuronal circuits in your brain enable that? And why do we have to lose such a precious memory when we get old?
My lab is investigating circuit mechanism of sensory perception and memory, using rodents as model organisms. We are also clarifying what neural circuits are affected and how the impairments of neuronal activities cause memory loss in Alzheimer’s disease.