The Cognitive Neuroscience of Sleep lab uses neuroimaging, behavioral manipulations, and computational methods to explore memory reactivation during sleep, which broadly impacts cognition, emotion, and health. Exploring the mechanisms through which sleep shapes human behavior requires a multi-disciplinary approach, combining neuroscientific, psychological, and computational methods. Our lab combines novel techniques to selectively bias memory reactivation; machine-learning algorithms to decipher memory-related content from neural data; and neuroscientific methods for monitoring brain connectivity and rhythms in different regions and timescales. Using this state-of-the-art methodological framework, the lab hopes to reveal the neural infrastructure through which sleep transforms memories, and how these dynamics may be harnessed for improving well-being in healthy and clinical populations.